The incident, which left six people sustaining serious injuries, happened at around 1.50pm on Saturday (16/7) on the Beaconsfield Eastern Relief Road, between the Pyebush roundabout (A40) and the A355 Amersham Road.
A black Audi was involved in a collision with a silver Range Rover.
The six injured people were taken to hospital where they are in a stable condition.
Investigating officer Sergeant Tyrone Powell, of the Buckinghamshire Roads Policing Unit, said: “If anybody witnessed this collision or has any information to give, please call 101 or make a report online on the TVP website, quoting reference 43220314354.
“We are particularly keen to hear from anybody who may have any dash-camera or mobile phone footage of this incident.”

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